Short Answer: Technically Yes.

Long Answer: But it is probably not what you want. If the game cannot find a valid weapon point for a weapon in the proper direction, it will spawn the weapon effect from the center of the ship. I had to edit the mesh to get the Ankylon's beams to fire 270 degrees from the spots the other beams fired from.

However, you don't need to open a fancy modeling program. Just get the reference files and open it in notepad. With a lot of trial and error you can usually figure out wish weapon points you want to change the orientation off and change them and/or duplicate them in another direction.