I made the unfortunate mistake of not locking teams on my first 8 player map with AI on hard. I ended up with one or two key planets always being attacked. As a result, I had my entire fleet there with 7 repair platforms. Unfortunately, while I was holding off the enemy AI, I wasn't taking any worlds, I was distracted from my economy, and I wasn't doing missions. All of that combined to result in my allies going rogue. From there it was all downhill. I ended up wiping out an enormous amount of ships, and even a few of my allies fleets, at a modestly high cost.
At that point, I knew I was in trouble, but I figured if it could wipe out pink, who was right next to me and had only a planet and asteroid field, I could cut down my exposed flanks and start building up my economy. It would take awhile, but I'd win. Pink, however, was having nothing to do with this idea. Pretty soon, I've all but taken his asteroid field, and his fleet starts showing up from where-ever the heck it had been. Even though I was in 8th place for fleet size and had foolishly tried to play with no capital ships (not my best move), I was still winning against him, and even drove off an assault or two for the first few minutes thanks to my insane number of repair platforms. Then things got ugly. His friends showed up.
I was still trying to lock down that asteroid field when suddenly I was being steamrolled. Of course, things being as they were, it wasn't just pink's allies (and, by extension, MY old allies) come to call. It was everyone else and their grandmother too. So, at that point, with 3 different planets under attack by forces that completely outnumbered them even without the capital ships, a fleet already in tattered ruins, and ailing repair platforms, it was pretty evident that I was, well, screwed. And not in the good way. I surrendered, and checked the stats. It turns out that I had done rather well, even with as many mistakes as I'd made. I had at least a 2-1, possibly 3-1, kill to death ratio, and had killed about 10 capital ships, close to twice as many as anyone else had destroyed.
Being stubborn, I'm now trying to beat this match from a save point about an hour or so in, where my allies are still allies, my enemies are still enemies, and my fleet and economy still suck. That said, as I discovered yesterday (my second time through, after a few weeks hiatus), it's not impossible to complete missions, you just have to pick and choose when. I'm trying to keep them all above 80%, which isn't as hard as it sounds. The map is pretty open ended, even though I can't recall what it's name is, which gives me tons of places to defend but also tons of places to slip through, hit them in the rear, then run away.
The hard part is getting enough ships freed up to complete missions without losing them and weakening my defenses irrepairably. I ended up getting steamrolled by a huge enemy fleet that I didn't have a fleet big enough to defeat (3 enemy AIs sent practically their entire fleets. Go figure). The bad part is, even with major elements of 3 entire enemy fleets busy, my allies still didnt take the initiative to either defend my massively outnumbered defenses or launch a big counterattack elsewhere. We'll see what happens when I try again today...